Table 1.

AP-1 family members alter the transformation potential of v-Rel in splenic lymphocytes

	Relative Colony Formation 1
Retrovirus	Exp. 1	Exp. 2	Exp. 3	Exp. 4	Exp. 5	Exp. 6	Avg ± Std. Dev.	p-value
BIS-V	100	100	100	100	100	100	100 ± 0
BIS-V+c-fos	414	382	199	448	589	-	406 ± 140	0.008
BIS-V+c-jun	311	332	172	297	364	-	295 ± 73	0.004
BIS-V + fra-2	156	130	104	707	238	-	267 ± 251	0.211
BIS-V + ATF2	43	44	37	12	77	43	43 ± 21	0.001

¹Splenic lymphocytes were infected with indicated retroviruses, plated in soft agar, and colonies were scored microscopically after 10 days. The number of colonies (ranging from 53 to 731) from BIS-V infections were normalized to 100 for each experiment. No colonies were observed with control BIS viruses or BIS viruses expressing AP-1 family members alone.