Table 1.
Body weight and composition of three T. cruzi-infected mouse groups
| Days Post-infection | Genotype | |||
|---|---|---|---|---|
| db/db | NSE-Rb db/db | FVB | ||
| Body Weight (g) | 0 | 60.36 ± 2.26 | 41.75 ± 0.40 | 21.60 ± 0.87 |
| 14 | 60.32 ± 2.34 | 40.73 ± 1.09 | 24.72 ± 0.72 | |
| 26 | 49.63 ± 2.72 | 39.50 ± 1.16 | 26.34 ± 0.82* | |
| Fat mass (g) | 0 | 31.50 ± 1.78 | 16.29 ± 1.89 | 3.92 ± 0.58 |
| 14 | 27.51 ± 1.60 | 11.85 ± 1.51 | 2.70 ± 0.44 | |
| 26 | 17.27 ± 2.03* | 5.95 ± 0.68* | 1.67 ± 0.23* | |
| Fat-free mass (g) | 0 | 27.92 ± 0.60 | 24.10 ± 1.26 | 16.46 ± 0.40 |
| 14 | 32.21 ± 0.74 | 28.14 ± 0.70 | 21.10 ± 0.36 | |
| 26 | 30.86 ± 1.00 * | 32.25 ± 1.27* | 21.55 ± 0.77* | |
- (p< 0.05)
There was a significant decease in body weight only in infected db/db mice. All groups experienced a significant reduction in reduction in fat mass and a significant increase in fat-free mass. Fat-free mass includes water and volume of visceral organs.