. Author manuscript; available in PMC: 2011 Aug 15.

Published in final edited form as: J Infect Dis. 2010 Aug 15;202(4):606–613. doi: 10.1086/654814

Table 2.

Allelic distribution and association tests of IL-10R1 polymorphisms in CMV retinitis cases and controls

Gene	SNP	European Americans								African Americans
		Allele Frequency (%)		Allelic		Codominant^a		Dominant^a		Allele Frequency (%)		Allelic		Codominant^a		Dominant^a
		Cases(n=200)	Controls (n=550)	OR	P	OR	P	OR	P	Cases(n=110)	Controls (n=424)	OR	P	OR	P	OR	P
IL10-R1^b
	rs3135932 (A/G)	17	14	1.21	0.23	1.27	0.18	1.39	0.11	2	3	0.72	0.49	0.72	0.54	0.72	0.54
	rs2228055 (A/G)	7	5	1.49	0.11	1.55	0.14	1.55	0.16	0.5	2	0.24	0.13	0.24	0.20	0.24	0.20
	rs4252279 (C/T)	9	11	0.81	0.31	0.79	0.26	0.87	0.60	11	11	1.00	0.99	0.99	0.97	0.98	0.94
	rs4252314 (A/G)	3	4	0.68	0.26	0.66	0.27	0.59	0.21	0.5	1	0.48	0.48	0.56	0.61	0.56	0.61
	rs4252286 (G/A)	4	2	1.61	0.15	1.95	0.08	1.95	0.08	0.9	0.4	2.50	0.28	1.22	0.84	1.22	0.84
	rs2229113 (G/A)	30	29	1.03	0.81	1.08	0.61	1.19	0.35	19	20	1.07	0.74	1.02	0.92	1.07	0.75
	rs2229114 (C/T)	2	5	0.44	0.03	0.42	0.03	0.42	0.04	2	0.6	3.25	0.06	1.61	0.60	1.61	0.60

Logistic regression model results adjusted for square root of nadir CD4+ T-cell count, log₁₀HIV-1 load, age, gender and HAART.

rs3135932, rs2228055, rs2229113, rs2229114 are also know as SNP3, SNP6, SNP4 and SNP8, respectively in literature [19]. rs2229113 and rs2229114 were previouslt examined for AIDS progression association [24].