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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Oral Oncol. 2010 Jul 24;46(9):648–653. doi: 10.1016/j.oraloncology.2010.06.011

Table 1.

Angiogenic polypeptides (selected examples)

Angiogenic proteins Endothelial mitogenicity Endothelial mobility Reference
Acidic fibroblast growth factor (aFGF) + + 29
Angiogenin (ANG) + + 30
Basic fibroblast growth factor (bFGF) + + 31
Epidermal growth factor (EGF) + + 32
Follistatin + + 33
Leptin + + 34
Midkine and pleiotrophin + + 35
Platelet-derived endothelial cell growth factor (PD-ECGF) + - 36
Vascular endothelial growth factor (VEGF) + + 37
Placental growth factor (PlGF) + + 38
Hepatocyte growth factor (HGF) + + 39
Platelet-derived growth factor (PDGF) + + 40
Platelet activating factor (PAF) - + 41
Interleukin-8 (IL8) + + 42
Granulocyte-colony stimulating factor (GCSF) + + 39
Proliferin - + 43
Tat protein of HIV-1 + + 44
Insulin-like growth factor (IGF) + - 45
Tumor necrosis factor-α (TNF-α) - - 46
Transforming growth factor-β (TGF-β) - - 47