Table 1.

Dissociation constants (K_d) for the interaction of α₂-antiplasmin with surface-adsorbed fibrinogen, fibrin, and their fragments obtained by ELISA.

Proteins/Fragments	Kd (nM)a
		+ εACA	+ tPA	+ plasminogen
fibrinogen	179 ± 19	102 ± 4	-	-
fibrin	102 ± 4	101 ± 12	109 ± 9	25 ± 2
E3 fragment	n. b.b	-	-	-
D1 fragment	197 ± 33	165 ± 11	-	-
D-D fragment	94 ± 4	98 ± 10	105 ± 4	5.5 ± 0.4
Aα221–610 fragment	131 ± 25	-	-	-
Aα392–610 fragment	150 ± 5	141 ± 14	157 ± 21	111 ± 14
Aα221–391 fragment	n. b.	-	-	-
Aα392–503 fragment	n. b.	-	-	-
Aα504–610 fragment	123 ± 10	130 ± 15	-	-

^aValues are means ± the standard deviation of at least three independent experiments.

^bNo binding was observed.