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. Author manuscript; available in PMC: 2011 Oct 10.
Published in final edited form as: Virology. 2010 Jul 27;406(1):80–87. doi: 10.1016/j.virol.2010.07.008

Figure 2. Administration of PIKA protected mice from lethal challenge and initiated influenza-specific antibody responses.

Figure 2

(A–B) Groups of five mice each were given PIKA or PBS as previously described and challenged with 4 LD50 of A/Puerto Rico/8/34 intranasally. The mice continued to receive PIKA treatment once a day for two additional days. Weight loss and survival rate was monitored for 2 weeks. (C) Serum samples were collected from PIKA-treated mice on day 14 post-infection and influenza-specific antibody titers were determined by ELISA.