Table 1.
Variable | SVR Group (n=140) | BT/R Group (n=77) | NR Group (n=309) | p-value* | |||
---|---|---|---|---|---|---|---|
N or mean | % or SD | N or mean | % or SD | N or mean | % or SD | ||
Age (years) | 48.6 | 6.1 | 48.6 | 5.7 | 49.6 | 7.6 | 0.23 |
Gender | |||||||
Male | 107 | 76.4% | 57 | 74.0% | 215 | 69.6% | 0.30 |
Female | 33 | 23.6% | 20 | 26.0% | 94 | 30.4% | |
Race/ethnicity | |||||||
White | 112 | 80.0% | 62 | 80.5% | 209 | 67.6% | 0.001 |
Black | 8 | 5.7% | 3 | 3.9% | 61 | 19.7% | |
Hispanic | 15 | 10.7% | 10 | 13.0% | 28 | 9.1% | |
Others | 5 | 3.6% | 2 | 2.6% | 11 | 3.6% | |
Stratum | |||||||
Fibrosis | 111 | 79.3% | 53 | 68.8% | 177 | 57.3% | <0.0001 |
Cirrhosis | 29 | 20.7% | 24 | 31.2% | 132 | 42.7% | |
Ishak fibrosis score | 3.6 | 1.2 | 3.9 | 1.2 | 4.2 | 1.3 | <0.0001 |
Steatosis score | 1.2 | 0.88 | 1.1 | 0.96 | 1.4 | 0.84 | 0.02 |
Genotype 1 | |||||||
Yes | 101 | 72.1% | 65 | 85.5% | 291 | 94.5% | <0.0001 |
No | 39 | 27.9% | 11 | 14.5% | 17 | 5.5% | |
Genotype 3 | |||||||
Yes | 14 | 10.0% | 5 | 6.6% | 8 | 2.6% | 0.004 |
No | 126 | 90.0% | 71 | 93.4% | 300 | 97.4% | |
Body Mass Index (BMI) | 29.3 | 5.5 | 29.4 | 5.3 | 30.2 | 5.7 | 0.16 |
WBC ×1000/mm3 | 6.17 | 2.1 | 5.98 | 1.98 | 5.62 | 1.73 | 0.01 |
Hemoglobin, g/dL | 15.5 | 1.35 | 15.1 | 1.43 | 14.9 | 1.38 | 0.001 |
Platelet count ×1000/mm3 | 180.2 | 59.2 | 180.7 | 55.8 | 164.2 | 70.5 | 0.02 |
Creatinine, mg/dL | 0.85 | 0.14 | 0.85 | 0.16 | 0.84 | 0.17 | 0.62 |
AST, U/L | 89.1 | 54.1 | 93.6 | 76.5 | 89.2 | 57.9 | 0.83 |
ALT, U/L | 137.5 | 83.5 | 132.2 | 112.9 | 112.0 | 79.6 | 0.008 |
Alk Phos, U/L | 88.3 | 36.8 | 87.8 | 31.7 | 102.3 | 47.8 | 0.001 |
T. Bilirubin, mg/dL | 0.74 | 0.34 | 0.79 | 0.40 | 0.78 | 0.36 | 0.45 |
Albumin, g/dL | 4.04 | 0.37 | 3.94 | 0.34 | 3.84 | 0.39 | <0.0001 |
INR | 1.02 | 0.09 | 1.02 | 0.09 | 1.04 | 0.11 | 0.04 |
AFP, ng/ml | 7.9 | 14.2 | 7.70 | 10.6 | 18.2 | 27.5 | <0.0001 |
p-value for comparison of the 3 groups.