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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Hepatology. 2010 Sep;52(3):833–844. doi: 10.1002/hep.23744

Table 4.

Cox proportional hazard analysis for death from any cause or liver transplantation (Model 1), and for liver-related morbidity and mortality (Models 2–5).

Model 1 Death (any cause) or Liver Transplantation Model 2 Any liver-related outcome Model 3 Decompensated liver disease Model 4 HCC Model 5 Liver-related death or Liver Transplantation

N=526 (72 events) N=526 (91 events) N=526 (50 events) N=526 (35 events) N=526 (55 events)

Variables Hazard Ratio 95% CI Hazard Ratio 95% CI Hazard Ratio 95% CI Hazard Ratio 95% CI Hazard Ratio 95% CI

Age (per 1 year) 1.05 1.01–1.10*

Baseline Platelets (per 10,000/mm3) 0.88 0.83–0.92* 0.85 0.81–0.89* 0.86 0.80–0.92* 0.85 0.79–0.92* 0.86 0.81–0.92*

Baseline albumin (per 0.1 g/dL) 0.89 0.83–0.94* 0.91 0.87–0.96* 0.90 0.83–0.96* 0.88 0.83–0.95*

Baseline alk phos (per 10 U/L) 1.08 1.02–1.13*

Baseline AFP (per 10 ng/ml) 1.06 1.01–1.12*

Treatment Response
 BT/R vs. NR 0.29 0.10–0.79* 0.46 0.22–0.96* 0.57 0.22–1.46 0.96 0.36–2.54 0.43 0.15–1.21
 SVR vs. NR 0.17 0.06–0.46* 0.15 0.06–0.38* 0.13 0.03–0.53* 0.19 0.04–0.80* 0.12 0.03–0.48*

The following variables were not significant in any model: race, stratum (fibrosis vs. cirrhosis), and AST/ALT ratio