. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: Hum Mutat. 2010 Sep;31(9):1050–1058. doi: 10.1002/humu.21314

Table 3.

SNPs significantly associated with telomere length after FDR correction

Gene	SNP ID	Genomic position		Minor Allele	MAF (%)	Beta^†	SE	P_trend	P_adj^‡
MEN1	rs669976	Chr11:64330165	intronic (IVS8+115)	C	10.05	−0.042	0.018	0.017	0.022
MEN1	rs524386	Chr11:64341535	downstream	C	8.95	−0.04	0.018	0.028	0.028
MEN1	rs2957154	Chr11:64341563	downstream	G	25.23	−0.036	0.012	0.003	0.014
MEN1	rs670358	Chr11:64348255	downstream	A	10.47	−0.046	0.017	0.007	0.014
RECQL5	rs820152	Chr17:71127683	upstream	C	37.74	−0.029	0.010	0.006	0.025
MRE11A	rs12270338	Chr11:93787112	upstream (*5826)	A	21.61	0.036	0.012	0.004	0.025
MRE11A	rs13447720	Chr11:93804974	intronic (IVS18−2174)	G	22.73	0.037	0.012	0.003	0.025
TNKS	rs11991621	Chr8:9443992	upstream	T	17.68	−0.042	0.014	0.002	0.029
TNKS	rs12549064	Chr8:9479437	intronic (IVS2+4134)	C	17.67	−0.041	0.014	0.003	0.029
TNKS	rs10903314	Chr8:9504516	intronic (IVS2−5986)	T	24.69	−0.034	0.012	0.005	0.039
TNKS	rs6990300	Chr8:9585271	intronic (IVS5+9551)	G	32.04	−0.031	0.011	0.006	0.039
TNKS	rs11249943	Chr8:9645273	intronic (IVS18-1256)	C	19.17	−0.035	0.013	0.009	0.049
TNKS	rs17150478	Chr8:9678444	downstream	G	18.77	−0.042	0.013	0.002	0.029

^†

All analysis were done using linear regression models with telomere length continuous, adjusted for gender, age, smoking status, principal components, and case/control status

MAF = minor allele frequency

SE = standard error

^‡

False Discovery Rate (FDR) corrected P-value