Table 2.
Baseline and clinical characteristics of non-alcoholic steatohepatitis patients regarding different sex and age groups (mean ± SD)
| Variable | Total (n = 77) |
Sex groups |
P-value |
Age groups |
P-value | ||
| Male (n = 58) | Female (n = 19) | < 55 yr (n = 65) | ≥ 55 yr (n = 12) | ||||
| Age (yr) | 41.99 ± 11.80 | 39.74 ± 10.16 | 48.72 ± 13.99 | 0.004a | - | - | - |
| Gender, n (%) | |||||||
| Female | 19 (24.7) | - | - | - | 14 (21.5) | 5 (41.6) | 0.214 |
| Male | 58 (75.3) | 51 (78.5) | 7 (58.4) | ||||
| BMI (kg/m2) | 28.62 ± 3.42 | 28.86 ± 3.25 | 27.81 ± 4.00 | 0.336 | 28.74 ± 3.55 | 26.87 ± 2.52 | 0.186 |
| Fasting blood sugar (mg/dL) | 107.37 ± 47.60 | 103.16 ± 47.39 | 121.14 ± 47.14 | 0.195 | 107.88 ± 52.06 | 114.12 ± 25.85 | 0.742 |
| Total cholesterol (mg/dL) | 197.29 ± 47.81 | 192.07 ± 45.52 | 212.68 ± 52.26 | 0.105 | 197.07 ± 46.98 | 200.67 ± 37.82 | 0.827 |
| Triglyceride (mg/dL) | 202.26 ± 118.13 | 201.72 ± 97.26 | 203.89 ± 169.65 | 0.947 | 206.40 ± 121.92 | 202.33 ± 100.36 | 0.876 |
| LDL-cholesterol (mg/dL) | 119.09 ± 39.20 | 119.87 ± 35.00 | 117.13 ± 49.64 | 0.822 | 118.27 ± 38.74 | 134.43 ± 40.13 | 0.313 |
| HDL-cholesterol (mg/dL) | 46.61 ± 24.53 | 44.97 ± 25.20 | 50.87 ± 22.97 | 0.301 | 47.86 ± 26.45 | 40.12 ± 13.68 | 0.891 |
| PTT (s) | 12.47 ± 1.50 | 12.39 ± 1.66 | 12.72 ± 0.86 | 0.846 | 12.45 ± 1.58 | 12.40 ± 1.52 | 0.842 |
| Platelet count (/L) | 358 505 ± 48 852 | 357 505 ± 52 403 | 361 125 ± 39 954 | 0.122 | 395 325 ± 55 385 | 237 385 ± 63 753 | 0.964 |
| ALT (U/L) | 117.73 ± 237.52 | 92.05 ± 60.72 | 196.11 ± 466.82 | 0.943 | 123.21 ± 260.49 | 100.44 ± 91.57 | 0.772 |
| AST (U/L) | 58.29 ± 27.77 | 52.78 ± 25.00 | 75.11 ± 29.68 | 0.002a | 57.28 ± 28.17 | 57.89 ± 20.52 | 0.951 |
| Alk-P (U/L) | 176.48 ± 96.95 | 171.14 ± 92.19 | 192.21 ± 111.00 | 0.417 | 176.11 ± 94.50 | 183.44 ± 128.40 | 0.837 |
| γ-GTP (U/L) | 29.55 ± 28.40 | 28.69 ± 30.95 | 31.42 ± 24.47 | 0.852 | 28.74 ± 3.55 | 15.17 ± 3.76 | 0.333 |
a
Statistically significant. BMI: Body mass index; LDL: Low density lipoprotein; HDL: High density lipoprotein; PTT: Partial thromboplastin time; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; Alk-P: Alkaline phosphatase; γ-GTP: γ-glutamyl transpeptidase.