Table 4.
Results of HPV-typing with pyrosequencing
Cases – 370 smears |
Controls – 747 smears |
|||
---|---|---|---|---|
n | % | n | % | |
Multiple infections | ||||
Total | 16 | 4.32 | 15 | 2.01 |
Two types | 9 | 2.43 | 8 | 1.07 |
Three types | 4 | 1.08 | 2 | 0.27 |
Four types | 2 | 0.54 | 4 | 0.54 |
Five types | 1 | 0.27 | 1 | 0.13 |
HPV type | ||||
16 | 16 | 4.32 | 25 | 3.35 |
18 | 6 | 1.62 | 9 | 1.20 |
31 | 7 | 1.89 | 8 | 1.07 |
33 | 16 | 4.32 | 9 | 1.20 |
35 | 5 | 1.35 | 2 | 0.27 |
45 | 5 | 1.35 | 3 | 0.40 |
51 | 6 | 1.62 | 1 | 0.13 |
52 | 3 | 0.81 | 1 | 0.13 |
56 | 7 | 1.89 | 5 | 0.67 |
58 | 1 | 0.27 | 2 | 0.27 |
59 | 2 | 0.54 | 2 | 0.27 |
The total number of types exceeds the number of HPV-positive smears as some smears contain multiple infections. There are no significant differences between cases and controls when n for individual HPV-types were compared with the number of HPV-positives in each category.