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Cumulative Age of Onset of Colorectal Cancer in Primary- and Secondary-Zone Relatives in Families Fulfilling Amsterdam-I Criteria and Distribution of Colorectal Cancer Diagnoses in the SEER Registry9
Curves exclude the 3 affected family members used to define the Amsterdam-I criteria. MSI-H indicates microsatellite instability–high; MSI-L, microsatellite instability–low; MSS, microsatellite stable; SEER, Surveillance, Epidemiology, and End Results.
