Table 3.
Regression Coefficients (β) (and SE), Odds Ratios (and 95% Confidence Intervals), and Nominal Significance Levels for Potentially Predictive Factors for MSI-H, Derived From Multiple Linear Logistic Regression Using the North American Data
Pathology | β (SE) | Odds ratio (95% confidence interval)a |
P value |
---|---|---|---|
Baseline | −4.31 (0.32) | < .001 | |
Diagnosis before age 50 years | 0.67 (0.25) | 2.0 (1.2–3.2) | .007 |
Right-sided | 1.64 (0.26) | 5.2 (3.1–8.6) | < .001 |
Mucinous or other | 1.06 (0.30) | 2.9 (1.6–5.2) | < .001 |
Poorly differentiated | 0.61 (0.26) | 1.8 (1.1–3.1) | .02 |
Crohn’s-like lymphocytic reaction | 0.54 (0.26) | 1.7 (1.0–2.8) | .04 |
Tumor-infiltrating lymphocytes | 2.09 (0.26) | 8.1 (9.9–13.4) | < .001 |
Adjusted for all other features.