Table 4.
The Distribution of Australian Cases by MsPath Score Categories, and the Probability of Tumor Being MSI-H, as Predicted by the MsPath Model
Sensitivity (%) | Specificity (%) | ||||
---|---|---|---|---|---|
MsPath score |
Probability tumor being MSI-H (%) |
Distribution (%) of cases younger than 50 years (n) |
Distribution (%) of cases 50–59 years (n) |
(if MSI test all tumors exceeding MsPath score) |
|
0.0a | 1 | 0 (0) | 47 (91) | 98 | 28 |
0.1–0.9 | 1–3 | 41 (69) | 10 (20) | 93 | 55 |
1.0–1.9 | 4–8 | 13 (22) | 19 (37) | 88 | 73 |
2.0–2.9 | 9–20 | 22 (38) | 13 (24) | 71 | 91 |
3.0–3.9 | 21–40 | 10 (17) | 4 (7) | 57 | 96 |
4.0–4.9 | 41–64 | 8 (13) | 6 (11) | 21 | 99 |
5.0–5.9 | 65–83 | 4 (7) | 1 (2) | 7 | 100 |
6.0–6.6b | 84–91 | 2 (3) | 0 (0) | 0 | 100 |
Total | 100 (169) | 100 (192) |
Minimum score.
Maximum score.