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Frequency of Alu Y transcripts in buffy coat cells of healthy humans and cases with neurodegenerative diseases. Numbers of Alu Y RNA/cDNA clones obtained from healthy controls, dementia and Alzheimer disease cases are shown in (A) and sporadic CJD are shown in (B). The prion protein genotypes are either homozygous or heterozygous for methionine or valine: M/M, V/V or M/V.
