| Hox genes whose expression is modulated by ECM |
|
| Hoxb9 |
Expression decreased in α5 integrin null mice [52] |
| Hoxa1, b7 |
Expression is suppressed by basement membrane ECM [43•] |
| HOXD3 |
Expression is suppressed by basement membrane ECM [37•] |
| Cdx2 |
Expression is induced by basement membrane [53•] |
| Dlx5 |
Expression is upregulated by mineralized ECM [54] |
| Hox gene expression and influence on cell–ECM interactions |
|
| Evx-1 |
Causes increased expression of tenascin [34] |
| Hoxa1 |
Expression correlates with laminin expression [32,35] |
| Cdx2 |
Causes increases laminin and β4 integrin expression [53•] |
| Hoxd3, HOXD3 |
Causes upregulation of β3 integrin expression [37•,55] |
| Hoxc10, 11, 13 |
Cause decreased surface expression of α2β1, α5β1 and α6β1 [44] |
