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. Author manuscript; available in PMC: 2010 Sep 3.
Published in final edited form as: Cancer Invest. 2002;20(1):139–153. doi: 10.1081/cnv-120000374

Figure 1.

Figure 1

Architecture of the basement membrane and cell surface connections. Basement membrane is composed of interconnected networks of collagen IV, laminin, nidogen/entactin, and proteoglycans such as perlecan. These connect to the cell through cell surface receptors such as integrins and dystroglycan. These, in turn, connect to the actin cytoskeleton through cytoplasmic adapter protein complexes.