Table 1. Foldchange of Gene Expression at Each Timepoint in CS-Stimulated Cells Compared to Unstimulated Cells.
Day 0 | Vac+7 | Vac+28 | |
IFN-γ median foldchange (range) | 0.9 (0.4–1.8) n = 12 | 2.7 (1.1–29.7) n = 12 | 1.5 (0.8–3.7) n = 9 |
FoxP3 median foldchange (range) | 0.8 (0.6–1.5) n = 12 | 1.5 (0.7–2.5) n = 9 | 0.9 (0.7–3.3) n = 10 |
MIG median foldchange (range) | 3.4 (0.2–7.7) n = 12 | 7.9 (0.6–25.4) n = 9 | 1.4 (0.3–11.2) n = 10 |
IL-10 median foldchange (range) | 0.8 (0.2–2.6) n = 11 | 0.6 (0.1–1.8) n = 8 | (0.6–2.0) n = 11 |
TGF-β1 median foldchange (range) | 1.1 (0.5–1.8) n = 12 | (0.0–1.8) n = 11 | 1.1 (0.8–2.2) n = 12 |
Day 0 = baseline prior to vaccination.
Vac+7 = seven days after the final vaccination.
Vac+28 = 28 days after the final vaccination.