Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Sep 10;87(3):325–340. doi: 10.1016/j.ajhg.2010.07.021

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 The American Society of Human Genetics. Published by Elsevier Ltd. All right reserved.

This document may be redistributed and reused, subject to certain conditions.

PMC Copyright notice

KSA Performance in Simulation

(A) The LD (measured by r²) pattern of simulated data from the Hapmap data. To show the block structure clearly, we show only the LD of the first 500 SNPs here. The LD block structure of all 2000 SNPs is very similar.

(B) Comparison of the values $2 ({\hat{L}}_{S} - {\hat{L}}_{K S A})$ and $2 ({\hat{L}}_{S} - {\hat{L}}_{H})$ based on KSA and log-linear models. KSA overestimation $2 ({\hat{L}}_{S} - {\hat{L}}_{H}) \leq 2 ({\hat{L}}_{S} - {\hat{L}}_{K S A})$ is illustrated here. For the region [25, + ∞), $2 ({\hat{L}}_{S} - {\hat{L}}_{K S A})$ is almost identical to $2 ({\hat{L}}_{S} - {\hat{L}}_{H})$ .