Figure 4.

Region of Homozygosity on Chromosome 5 Common to Six Affected Individuals from Four Consanguineous Families

Black and yellow bars indicate homozygous and heterozygous SNPs, respectively. Isolated heterozygous SNPs within larger homozygous segments are likely to represent miss-calls. The SNP-barren interval (gray region in center of right image) represents a 500 kb inverted duplication on chromosome 5q13. The common region of homozygosity defining the critical interval lies between 67,789,350-74,259,390 base pairs. Information is derived from AutoSNPa.³⁶ Listed in Table 1.