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. 2010 Sep 10;87(3):354–364. doi: 10.1016/j.ajhg.2010.07.012

Figure 7.

Figure 7

Occludin In Situ Hybridization Expression in Adult Mouse Brain

(A–C) Sagittal images from C57BL/6J mice at 55 days. Occludin is expressed throughout the brain, particularly in the cerebral cortex and cerebellum (B). Magnified images (boxed) of cerebral cortex (A) and cerebellum (C) showing marked occludin expression in layers 2 and 3 of the cerebral cortex and in the Purkinje cell layer in the cerebellum (arrows). Images from the Allen Mouse Brain Atlas, Section ID 79394328_12.

(E–H) Whole-brain sagittal images (E, G) and higher magnification of sections of cerebral cortex (F, H). Claudin 5 expression appears to be concentrated in cerebral blood vessels (E, F). Tubb2b is expressed throughout the brain and concentrated in the cerebral cortex and cerebellum (G, H) in a similar distribution to occludin (B, A). Images from the Allen Mouse Brain Atlas, Section IDs 79360268_14 (E, F) and 69854163_14 (G, H).