Table 2.
Patient | F085a1 (1) | F085a1 (2) | F085a1 (3) | F085a2 | F312a1 | F375a1 | F386a1 |
---|---|---|---|---|---|---|---|
Age | 1 month | 3 months | 4 months | 6 months | 1 week | unknown | 3 days |
White cell count | 9/μL (0–5/μL) | 4/μL (0–5/μL) | 2/μL (0-5/μL) | 1/μL (0-5/μL) | 1/μL (0-5/μL) | normal (value not available) | 2/μL (0-5/μL) |
Protein | 1021 mg/L (100–200 mg/L) | 824 mg/L (100–200 mg/L) | 666 mg/L (100–200 mg/L) | 631 mg/L (100–200 mg/L) | 60 mg/L (40–400 mg/L) | 700 mg/L (100–200 mg/L) | 1260 mg/L (200–600 mg/L) |
Glucose | 3 mmol/L (2.2–3.9 mmol/L) | 2.7 mmol/L (2.2–3.9 mmol/L) | - | 64 mg/dL (40–70 mg/dL) | - | - | 79 mg/dL (50–80 mg/dL) |
Lactate | 1.1 mmol/L (<2.1 mmol/L) | 1.3 mmol/L (<2.1 mmol/L) | 1.5 mmol/L (<2.1 mmol/L) | 1.0 mmol/L (<2.1 mmol/L) | 2.2 mmol/L (<2.1 mmol/L) | - | - |
CSF IFNα | normal | - | - | - | - | - | - |
Serum IFNα | normal | - | - | - | - | - | - |
CSF IgG | - | - | 26.6 mg/L | 37.8 mg/L | - | - | - |
Oligoclonal bands | - | - | negative | negative | - | - | - |
Normal values for each measurement are in parentheses. Cerebrospinal fluid (CSF) protein levels were raised in 4 of 5 individuals. Serial measurement of CSF protein in F085a1 showed a reduction in protein concentration over a 3 month period. All other measurements were normal. IFNα, interferon alpha; IgG, immunoglobulin G.