Table 2.
Amplitude of the b-wave of the photopic ERG from Nxnl1+/+ and Nxnl1−/− mice
Age | b-wave amplitude* (μV) +/− SEM | Time to peak (msecs) +/− SEM | ||
---|---|---|---|---|
+/+ | −/− | +/+ | −/− | |
3 months (n = 5) | 188.5 +/− 31.5 | 184.1 +/− 27.2 | 60.2 +/− 0.9 | 60.0 +/− 3.1 |
7 months (n = 5) | 129.2 +/− 6.9 | 98.2 +/− 14.0 | 68.6 +/− 12 | 65.2 +/− 2.0 |
12 months (n = 5) | 136.0 +/− 15.1 | 93.0 +/− 10.0 | 64.2 +/− 2.6 | 72.5 +/− 3.3 |
At 12 months p = 0.05 |
ERG voltage response recorded at 10 cds/m2 from light-adapted mouse retinas