Table II.

Genes linked to survival/apoptosis differentially expressed in normal B cells, normal and tumoral plasma cells

Genes overexpressed in MBC versus:	Ratio	MBC/PPC	Ratio	MBC/BMPC	Ratio	MBC/MMC
TNFRSF10A	3.2	P = .004	6.1	P = .003	5.2	P < .001
TNFRSF10B	4.3	P = .003	2.1	P = .007	1.8	P = .007
BCL2A1	7.8	P = .003	2.4	P = .007	3.9	P < .001
CASP8	1.9	P = .010	2.4	P = .002	2.3	P < .001
CASP9	2.2	P = .004	3.3	P = .001	2.7	P < .001
PMAIP1	5.6	P = .003	2.4	P = .003	2.9	P < .001
Genes overexpressed in PPC versus:	Ratio	PPC/MBC	Ratio	PPC/BMPC	Ratio	PPC/MMC
FAS	3.0	P = .003	3.1	P = .002	6.4	P < .001
FADD	2.2	P = .003	2.6	P = .002	2.4	P < .001
AIFM1	4.0	P = .004	5.7	P = .002	3.1	P < .001
BIRC5	44.8	P = .003	55.9	P = .002	22.2	P < .001
CASP2	2.1	P = .010	2.8	P = .002	2.2	P < .001
CASP3	9.1	P = .003	3.5	P = .002	3.9	P < .001
CASP6	4.9	P = .003	4.6	P = .002	3.8	P < .001
Genes overexpressed in BMPC versus:	Ratio	BMPC/MBC	Ratio	BMPC/PPC	Ratio	BMPC/MMC
BCL2	1.5	P = .046	5.3	P = .002	1.0	NS
MCL1	4.6	P = .003	1.7	P = .025	1.1	NS
BID	2.4	P = .003	2.0	P = .002	1.3	P = .007
BIRC3	1.8	P = .046	11.8	P = .002	1.5	P = .039
XIAP	3.0	P = .003	2.4	P = .003	1.8	P < .001
Genes overexpressed in MMC versus:	Ratio	MMC/MBC	Ratio	MMC/PPC	Ratio	MMC/BMPC
TNFSF10	7.7	P = .001	3.1	NS	2.1	NS
Genes underexpressed in MMC versus:	Ratio	MBC/MMC	Ratio	PPC/MMC	Ratio	BMPC/MMC
FAS	2.1	P = .001	6.4	P < .001	2.0	P = .001
APAF1	4.2	P < .001	5.4	P < .001	1.9	P = .002
BNIP3	1.0	NS	4.5	P < .001	2.8	P < .001

The ratios of the mean microarray signals in 6 BMC samples, 7 PPC, 7 BMPC and 92 MMC are indicated. P values are indicated. NS means “not significant”