Table 3.

Relationship between F₂-isoprostane Excretion and Clinical Factors in Patients with Rheumatoid Arthritis

Category	Factor	Rho(ρ)*	Unadjusted p-value	Adjusted p-value†
	Age	-0.33	<0.001	0.02
	BMI	0.35	<0.001	<0.001
	HDL Cholesterol	0.04	0.61	0.03
Cardiovascular Risk Factors	LDL Cholesterol	0.04	0.56	0.34
	Triglycerides	0.01	0.94	0.17
	HOMA Index	0.09	0.26	0.55
	Framingham Score	-0.13	0.10	0.74
	Disease Duration	-0.03	0.68	0.08
Disease-Related Indices and Inflammatory Mediators	DAS28 Index			0.52
		0.02	0.75
	Larsen Score**	0.025	0.75	0.04
	Neutrophil Count‡	0.16	0.04	0.51
	Monocyte Count‡	0.15	0.06	0.09
	TNF-α‡	-0.07	0.40	0.78
	IL-6‡	0.02	0.82	0.41
	CRP‡	0.06	0.41	0.66
	SAA‡	-0.06	0.47	0.43

^*Univariate Spearman correlation coefficient.

^**n=94.

^†Adjusted p-values are reported from multiple linear regression models adjusting for age, race, sex, hypertension, BMI and smoking.

^‡log-transformed.