Table 3.

Multivariable Linear Regression Model Predicting the Cognitive Change Score (Continuous Outcome) at 6-week Follow-up.

Variable	Parameter Estimate (95% confidence limits)	P value
Age	-0.004 [-0.008 - (-0.0005)]	0.03
Years of Education	0.009 [-0.001 - 0.020]	0.03
Preoperative cognitive index	-0.13 [-0.213 - (-0.054)]	0.001
Female sex	0.041 [-0.019 - 0.102]	0.18
Diabetes	-0.007 [-0.089 - 0.075]	0.87
Orthopedic surgery	-0.029 [-0.100 - 0.041]	0.41
General anesthesia	-0.013 [-0.075 - 0.048]	0.67
APOE4	-0.026 [-0.096 - 0.044]	0.47

APOE4 = Apolipoprotein E4