Table 2.
Genes having SNPs reaching P < 0.05 in glutamate metabolism pathway (BioCarta) in the GAIN GWAS dataset
| Gene symbol | SNP | Chromosome | Position | Region | P |
|---|---|---|---|---|---|
| GLS | rs1546646 | 2 | 191536841 | 3'UTR | 0.002 |
| GCLC | rs7758764 | 6 | 53504121 | Intron | 0.004 |
| CPS1 | rs4233981 | 2 | 211237623 | Intron | 0.005 |
| ALDH5A1 | rs7770041 | 6 | 24655330 | Downstream | 0.005 |
| GMPS | rs7651038 | 3 | 157134981 | Intron | 0.005 |
| GAD1 | rs10191129 | 2 | 171396839 | Intron | 0.007 |
| CAD | rs6759518 | 2 | 27340099 | Downstream | 0.011 |
| GAD2 | rs12243037 | 10 | 26564380 | Intron | 0.013 |
| GLUD1 | rs11202308 | 10 | 88789590 | Downstream | 0.014 |
| ABAT | rs12149040 | 16 | 8717353 | Intron | 0.037 |