Skip to main content
. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Cancer Res. 2010 Jun 15;70(13):5438–5447. doi: 10.1158/0008-5472.CAN-09-2544

Figure 4. Reactivation of PP2A dephosphorylates the c-KIT receptor and its downstream signaling targets.

Figure 4

A, c-KIT was immunoprecipitated from FDC-P1 cells treated with 2.5 μM FTY720 (0, 6, 12, 24 h). Levels of tyrosine phosphorylated (pY) and total c-KIT were determined by immunoblotting (top). Quantitation of three independent experiments (bottom). B, Immunoblots detecting phosphorylated or total Akt, STAT5, ERK1/2, p38MAPK, MEK and BAD after FTY720 treatment (2.5μM; 12h).