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. Author manuscript; available in PMC: 2011 Oct 13.
Published in final edited form as: Neuroscience. 2010 Jul 13;170(2):633–644. doi: 10.1016/j.neuroscience.2010.07.011

Figure 1. Aged rats display greater degree of neurodegeneration than young rats following MCAO.

Figure 1

MCAO results in neurodegeneration in both young and aged rats. Arrows show examples of Fluoro-Jade stained (degenerating) neurons. In young adult rats at 6 h post MCAO, neuronal damage was confined to ipsilateral striatum (A) and did not extend into cortex (B). In aged animals at 6 h post MCAO, neuronal damage was observed in both ipsilateral striatum (C) and cortex (D). By 24 h post MCAO in young animals, neurodegeneration was persistently observed in ipsilateral striatum (E) and appeared in ipsilateral cortex (F). Bar = 100 μ.

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