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. 2010 Jan-Mar;14(1):72–79. doi: 10.4103/0972-124X.65442

Table 1.

Tobacco induced periodontal tissue changes

Tissue changes with use Biologic bases for changes Tissue changes with abstinence
Paler tissue color Increased vasoconstriction Increased blood flow
Decreased bleeding Oxygen depletion Initially more bleeding, erythema
Thickened fibrotic consistency, minimal erythema relative to extent of disease Compromised immune response: Healthier consistency and anatomy
 Fewer and impaired PMNS
 Reduced IgG antibody
Gingival recession around anterior sextants Increased collagenase production
Greater probing depth, bone and attachment loss, furcation invasion Reduction of bone mineral, impaired fibroblast formation Stabilization of attachment levels
Refractory status Impaired wound healing