Table 1.
Tissue changes with use | Biologic bases for changes | Tissue changes with abstinence |
---|---|---|
Paler tissue color | Increased vasoconstriction | Increased blood flow |
Decreased bleeding | Oxygen depletion | Initially more bleeding, erythema |
Thickened fibrotic consistency, minimal erythema relative to extent of disease | Compromised immune response: | Healthier consistency and anatomy |
Fewer and impaired PMNS | ||
Reduced IgG antibody | ||
Gingival recession around anterior sextants | Increased collagenase production | |
Greater probing depth, bone and attachment loss, furcation invasion | Reduction of bone mineral, impaired fibroblast formation | Stabilization of attachment levels |
Refractory status | Impaired wound healing |