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. 2009 Oct 23;43(3):334–341. doi: 10.1165/rcmb.2009-0149OC

Figure 1.

Figure 1.

(A) Diagram of the constructs containing the alternative human exons −1a and 1a or sheep Ov1aS and Ov1aL exons joined to cystic fibrosis transmembrane conductance regulator (CFTR) exons 2–24. Vertical arrows denote putative alternative initiation codons (together with their location on AC000111 or AF325415, and the predicted amino acid [aa] length resulting from their usage). The ATGs in exons 3 and 4 are also shown. (B) Sequence of exons −1/1a joined to exon 2 and exon −1a joined to exon 2. Sequence of alternative exons is presented as following: exon −1a, Roman font; exon 1a, italics; exon 2, bold. The potential CTG and ATG initiation codons are marked in bold.