Table 2.
Cellular relative fluorescent intensity after the uptake and excretion of ADM.
| Cell | Cellular relative fluorescence intensity of ADM | Excretion rate of ADM (%) | |
|---|---|---|---|
| After Uptake | After Excretion | ||
| Bel-7402 (Parent) | 11.19 ± 0.23 | 7.37 ± 0.16 | 34.14 |
| Bel-7402/ADMS | 15.27 ± 0.22 | 5.87 ± 0.13 | 61.56 |
| Bel-7402/ADML | 15.61 ± 0.18 | 5.22 ± 0.13 | 66.56 |
| Bel-7402/ADMV | 19.11 ± 0.15 | 3.62 ± 0.17 | 81.06 |
| F | 1338.016 | 531.312 | |
| P | 0.000 | 0.000 | |
Note: By LSD paired-comparison after the uptake and excretion, drug-resistant cellular relative fluorescent intensity of ADM showed significant differences (P < 0.05).