Table 3.
Staining rate of P-gp, MRP and GSH/GST fluorescent cells analyzed by flow cytometry.
| Cell | Expression rate (%, ± s) | ||
|---|---|---|---|
| P-gp | MRP | GSH/GST | |
| Bel-7402 (Parent) | 19.59 ± 0.62 | 21.29 ± 1.14 | 26.92 ± 1.79 |
| Bel-7402/ADMS | 65.92 ± 1.41 | 56.88 ± 1.49 | 27.76 ± 1.00 |
| Bel-7402/ADML | 68.10 ± 1.88 | 58.84 ± 2.35 | 28.97 ± 1.42 |
| Bel-7402/ADMV | 91.93 ± 2.49 | 78.28 ± 1.23 | 27.57 ± 1.24 |
| F | 1512.300 | 1064.757 | 1.890 |
| P | 0.000 | 0.000 | 0.172 |
Notes: By LSD paired-comparison in both P-gp and MRP groups, except for Bel-7402/ADML vs. Bel-7402/ADMS (P > 0.05), there was no statistical significance. In other groups of resistant cells, there was a significant difference by paired-comparison (P < 0.01). In addition, for GSH/GST, there was no statistical significance by paired-comparison (P > 0.05).