Table 3.
Distribution of DNA damage and percent residual DNA damage among cases and current smoker controls
| Tail Extent Moment Mean ± SE |
Cases | Controls | P-value | Adjusted OR |
95% CL |
|---|---|---|---|---|---|
| Current Smokers |
Current Smokers |
||||
| H2O2 + OGG1 | 44.6 ± 0.89 | 18.4 ± 1.37 | <0.001 | ||
| Percent Residual Damage (PRD) | 237.4 ± 8.7 | 180.8 ± 50.7 | <0.001 | ||
| Residual Damage Logistic Regression (RDLR) | |||||
| ≤75th N (%) | 13(43.3) | 41(75.9 | |||
| >75th N (%) | 17(56.7) | 13(24.1) | |||
| 5.07 | 1.80-14.24 | ||||
| Referent | 5.07 | 1.80-14.24 | |||
P-value from t-test; TEM RDLR dichotomized by 75th percentile of the controls. Adjusted by age, sex and family history of a smoking-related cancer