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Trends in correlation between viral and human codon usage by year of viral isolation. (A) Correlation trend for human H1N1 and H3N2 subtypes and avian influenza. (B and C) Correlation of codon usage between H1N1 (B) or H3N2 (C) viral genes and genes expressed in human bronchial epithelial cells by year of virus isolation. The linear regression line and the correlation coefficient of each dataset are shown.
