Table 1.
Cell counts, plasma concentration of acute phase proteins and pro-inflammatory cytokines.
| Benjamini | ||||||
|---|---|---|---|---|---|---|
| HA (m±SD) | AIA (m±SD) | AIC (m±SD) | AIA vs AIC | AIA vs HA | AIC vs HA | |
| Cell counts (nb/μL) | ||||||
| Lymphocytes | 1531.76 ± 464.12 | 1086.58 ± 417.70 | 1442.65 ± 459.67 | p < 0.001 | p < 0.001 | p < 0.001 |
| Leucocytes | 5975.76 ± 998.45 | 10601.16 ± 4623.98 | 8083.78 ± 2379.13 | p < 0.001 | p < 0.001 | p < 0.001 |
| Neutrophils | 3762.94 ± 891.50 | 8734.72 ± 4284.35 | 5702.68 ± 2040.11 | p < 0.001 | p < 0.001 | p < 0.001 |
| Acute phase proteins | ||||||
| Albumin (mg/dL) | 4270.67 ± 443.31 | 2982.42 ± 483.71 | ND | p < 0.001 | ||
| Prealbumin (mg/dL) | 26.00 ± 4.74 | 10.69 ± 4.61 | ND | p < 0.001 | ||
| CRP (mg/dL) | 0.26 ± 0.41 | 18.34 ± 9.24 | 2.50 ± 3.45 | p < 0.001 | p < 0.001 | p < 0.001 |
| D-dimer (ng/mL) | 647.22 ± 430.54 | 2442.90 ± 1692.26 | 1838.14 ± 1125.11 | p < 0.05 | p < 0.001 | p < 0.05 |
| Fibrinogen (mg/dL) | 392.81 ± 65.54 | 752.09 ± 242.97 | 586.22 ± 172.04 | p < 0.01 | p < 0.001 | p < 0.005 |
| Pro-inflammatory cytokines | ||||||
| IL6 (pg/mL) | 14.01 ± 26.95 | 121.84 ± 98.73 | 56.28 ± 71.23 | p < 0.001 | p < 0.005 | p < 0.001 |
| IL10 (pg/mL) | 1.15 ± 3.67 | 17.95 ± 109.00 | ND | p < 0.001 | ||
| TNF alpha (pg/mL) | 22.80 ± 12.57 | 52.30 ± 45.88 | ND | p < 0.005 | ||
Values are expressed as mean ± SD. CRP: C-reactive protein; ND: Not Determined; Healthy Aged (HA); Aged patients with Infectious diseases in Acute phase (AIA); Aged patients with Infectious diseases in Convalescence phase (AIC).