Table 2.

Genes differentially expressed in PMBC of Aged patients with Infectious diseases in Acute phase (AIA) patients (n = 39) versus healthy aged (HA) probands (n = 28).

Gene Symbol	Gene Name	Accession Number	AIA/HA ratio	Benjamini
BCL2	B-cell CLL/lymphoma 2	NM_000633.1	0.58	p < 0.001
CASP8	Caspase 8, apoptosis-related cysteine peptidase	X98172.1	0.66	p < 0.001
CCL5	Chemokine (C-C motif) ligand 5	NM_002985.1	0.71	p < 0.001
CD28	CD28 antigen (Tp44)	NM_006139.1	0.61	p < 0.005
CD69	CD69 antigen (p60, early T-cell activation antigen)	NM_001781.1	0.44	p < 0.001
DDIT3	DNA-damage-inducible transcript 3	S40706.1	0.76	p < 0.01
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	D49547.1	0.76	p < 0.001
EGR3	Early growth response 3	NM_004430.1	0.42	p < 0.05
LCK	Lymphocyte-specific protein tyrosine kinase	NM_005356.2	0.58	p < 0.001
CLU	Clusterin	J02908.1	1.79	p < 0.001
CTSD	Cathepsin D (lysosomal aspartyl peptidase)	M11233.1	1.50	p < 0.001
CTSZ	Cathepsin Z	AF136273.1	1.33	p < 0.05
GPX1	Glutathione peroxidase 1	M21304.1	1.21	p < 0.05
HMOX1	Heme oxygenase (decycling) 1	NM_002133.1	1.57	p < 0.001
IL10RB	Interleukin 10 receptor, beta	NM_000628.3	1.39	p < 0.001
IL1R1	Interleukin 1 receptor, type I	NM_000877.2	1.48	p < 0.05
IL1R2	Interleukin 1 receptor, type II	U74649.1	2.34	p < 0.001
PRDX6	Peroxiredoxin 6	NM_004905.1	1.23	p < 0.005
PSMD1	Proteasome (prosome, macropain) 26 S subunit, non-ATPase, 1	NM_002807.1	1.24	p < 0.001
SERPINB2	Serpin peptidase inhibitor, clade B (ovalbumin), member 2	J02685.1	2.17	p < 0.005
SOD2	Superoxide dismutase 2, mitochondrial	NM_000636.1	1.53	p < 0.001
TIMP1	TIMP metallopeptidase inhibitor 1	NM_003254.1	1.71	p < 0.001
TIMP2	TIMP metallopeptidase inhibitor 2	NM_003255.2	1.59	p < 0.001
TNFRSF1A	Tumor necrosis factor receptor superfamily, member 1A	NM_001065.2	1.45	p < 0.001

Statistical analysis was carried out with the Mann-Whitney test.