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. 2001 Feb 13;98(4):1799–1804. doi: 10.1073/pnas.98.4.1799

Figure 3.

Figure 3

(A) A karyotype of the chromosomes of the Karpas 707H cell line, which are near-tetraploid. Note that chromosomes 2, 14, and 22, which contain the Ig genes, are normal and diploid. 83,XX,-X,-X,del(1)(p11p36)x4,+del(1)(q11q44),-2,-2,der(3)del(3)(p21p25)inv(3) (q23q25),+del(3)(q13q21),der(5)t(1;5)(p11;q31),der(5)t(2;5)(q21;q31), del(5)(q13q33)x2,+add(5)(q31),-6,-6,add(7)(p25),del(8)(q22q24),-9, del(11)(q23q25),-11,del(12)(p12p13),-13,-13,-14,-14,add(15)(p11)x2, der(16)t(1;16)(p11;p11),add(16)(p11)x2,-16,der(18)t(1;18)(q23;p11),add(18)(p11),add(18)(q23),-18,add(19)(q13)x2,+der(19)t(1;19)(q11;p13) +der(19)t(dup(1)(q23q44);19)(q11;p13),-21,-22,-22,+mar1 × 2,+mar2. (B) A karyotype of the hybridoma Karpas 707H/164, which is near-hexaploid, containing the normal pairs of chromosomes that are readily obvious in the case of chromosomes no. 1. 125,XXX,-X,-X,-X,del(1)(p11p36)x4,+del(1)(q11q44),-2,-2,add(3)(p25),der(3)del(3)(p21p25)inv(3)(q23q25),add(4)(q31),-4,der(5)t(1;5)(p11;q31), der(5)t(2;5)(q21;q31),del(5)(q13q33)x2,+add(5)(q31),del(6)(q21q23) -6, -6,add(7)(p25)x2,del(8)(q22q24),-9,del(11)(q23q25),-11, del(12)(p12p13)x2,-13,-13,-14,-14,add(15)(p11)x2,der(16)t(1;16)(p11;p11), add(16)(p11)x2, -16,der(18)t(1;18)(q23;p11),add(18)(p11),add(18)(q23), -18,add(19)(q13)x2,+der(19)t(1;19)(q11;p13),+der(19)t(dup(1)(q23q44);19)(q11;p13), -21,-21,-22, -22,+mar1 × 2,+mar2.