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. Author manuscript; available in PMC: 2011 Aug 27.
Published in final edited form as: Immunity. 2010 Jul 30;33(2):203–215. doi: 10.1016/j.immuni.2010.07.013

Figure 7.

Figure 7

IL4 was necessary for the innate-like phenotype on Id3−/ − CD8 thymocytes. (A) FACS analysis for IL4Rα on CD8 thymocytes from Id3−/ − (left), Id3−/ − Zbtb16lu/lu (middle) and Id3−/ −Il4−/ − (right) mice compared to WT (grey). (B) IL4Rα expression on WT minority cells that developed with a majority of WT (left) or Id3−/ − (right). Isotype control (shaded histogram). (C) Intracellular PLZF in CD8 thymocytes from mice of the indicated genotype compared to isotype control (shaded). (D) WT, IL4−/ −, Id3−/ − and Id3−/ −IL4−/ − thymocytes were analyzed for TCRβ (upper) and CD4 versus CD8 on TCRβ + thymocytes (lower). (E) CD8 thymocytes from mice of the indicated genotype (black) or WT mice (grey) were analyzed for CD122 (upper), CD44 (middle) or CD24 (lower). Grey histogram is WT CD8 thymocytes. Data are representative of > 4 experiments.