Table 2.

King's College Criteria for Poor Prognosis in ALF

Acetaminophen-induced ALF	Nonacetaminophen-induced ALF
Arterial pH <7.30 after fluid resuscitation	Prothrombin time >100 sec (INR >6.5)
Or all of the following: Prothrombin time >100 sec (INR >6.5) Serum creatinine >3.4 mg/dL Grade 3 or 4 hepaticencephalopathy	Or any 3 of the following: Non-A, non-B viralhepatitis, drug-induced orindeterminate etiology of ALF Time from jaundice→encephalopathy >7 days Age <10 years or >40 years Prothrombin time >50 sec (INR >3.5) Serum bilirubin >17.4 mg/dL

ALF=

acute liver failure;

INR=

international normalized ratio.