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Crosstalk and hormonal regulation of glucose and lipid sensing. This schematic representation of the interrelationship between glucose and lipid-sensing mechanisms and their modulation by hormones underlines the convergence of these signals on three key players: AMPK, malonyl-CoA, and KATP channels. LCFA-CoA long-chain fatty acyl-CoA, ACC acetyl-CoA carboxylase, FAS fatty acid synthase, CPT1 carnitine palmitoyltransferase 1
