Figure 2.

The Ca²⁺-dependent S100-target protein interactions. In red/blue are subunits of S100B (^dimerK_D< 500 pM [1, 17]) with regions shaded (yellow) for residues that bind targets such as p53^367-388 (green), p53 (p53^321-346, K_D = 24 ± 10 nM), or TRTK12 [10, 18].