Table 4.
Canonical Correlation Analysis Between Spirometry Variables and Clinical Variables Using Combined PACT and CLIC Baseline Data
| Combined PACT and CLIC Canonical Variate Pairs | |||
|---|---|---|---|
| Standardized Coefficients | |||
| Variate Pair 1 | Variate Pair 2 | Variate Pair 3 | |
| Diary AM PEF % Predicted | 0.32 | 0.82 | -1.43 |
| Diary PM PEF % Predicted | 0.05 | -0.22 | 1.94 |
| Max BD Response (% Change in FEV1) | -0.61 | 0.77 | -0.17 |
| log2(PC20) | 0.41 | 0.20 | -0.13 |
| Diary Symptoms (Cough and Wheeze) | 0.11 | 0.32 | -0.35 |
| Diary Rescue Albuterol Use | -0.01 | -0.14 | 0.07 |
| log10(Exhaled NO) | -0.01 | 0.07 | 0.46 |
| ACQ Score | -0.17 | -0.37 | 0.21 |
| Prior Hospitalizations | 0.07 | 0.08 | -0.31 |
| FEV1 % Predicted | 0.10 | 1.25 | 0.58 |
| FEF25-75 % Predicted | 0.88 | -1.40 | 0.83 |
| FEV1/FVC % Predicted | 0.06 | 0.58 | -1.54 |
| Canonical Correlation | 0.65 p < 0.0001 |
0.46 p < 0.0001 |
0.20 p = 0.23 |