Fig. 11.

Kinetics of hIAPP amyloid fiber formation monitored by 2D IR spectroscopy. (a) 2D IR spectrum of hIAPP ¹³C=¹⁸O-labeled at L16 average at 7 min. (left) and 187 min. (right) of aggregation. (b) Kinetics of diagonal features at ω_pump = ω_probe = 1589 cm⁻¹ (red), 1620 cm⁻¹ (green) and 1659 cm⁻¹ (blue), corresponding to the isotope label, β-sheet and random coil features, respectively.