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Time constant of rat rod b-wave recovery from bleach after acute isotretinoin (stimulus −3.4 log cd⋅s/m2)
| Exponential time constant (1/min) | P value* vs. isotretinoin | |
|---|---|---|
| No. animals | Mean (SD) | |
| Untreated (n = 4) | 0.0090 (0.0030) | <0.0001 |
| DMSO (n = 4) | 0.0089 (0.0041) | 0.0004 |
| Isotretinoin (n = 7) | 0.0006 (0.0004) | — |
| Recovery 3–6 d (n = 4) | 0.0095 (0.0032) | <0.0001 |
Student's two-tail t test; both eyes of each animal averaged.
