FIG 2 .

Capsule promotes resistance to neutrophil-mediated killing of GAS serotype M1T1. (A) Capsular hyaluronic acid quantification. Values denote arithmetic means plus standard errors (SEs) (error bars) and are representative of two independent experiments performed in triplicate. (B) Bacterial survival in total (intracellular plus extracellular) neutrophil killing assays. Values represent arithmetic means plus SEs and are representative of three independent experiments performed in triplicate. (C) Survival in extracellular neutrophil killing assays when phagocytic uptake is inhibited with cytochalasin D (10 µg/ml). Values denote arithmetic means plus SEs and are representative of three independent experiments performed in triplicate. Values that are statistically significantly different (P < 0.05) from the value for isolate 5448 (wild type [WT]) are indicated by an asterisk.