TABLE 1.

Quantitative representation of E2F1-responsive transcript levels in MCF-7 cells expressing either GRIM-19 and/or p16

Student's t-test was used to access the statistical differences. GRIM-19 and/or p16/GRIM-19-expressing cells were compared to p16-expressing cells.

Gene analyzed	Cell line pairs
	EV	p16	GRIM-19	p16/GRIM-19
	%	%	%	%
MCM4	100	96.3 ± 5.0	58.3 ± 0.9	24.9 ± 0.6
			(p < 0.01)	(p < 0.01)
MYBB	100	88.0 ± 11.4	74.1 ± 2.7	35.3 ± 4.4
			(p < 0.05)	(p < 0.01)
DHFR	100	67.0 ± 3.9	65.9 ± 8.0	13.8 ± 6.4
				(p < 0.01)
TK1	100	71.4 ± 8.0	50.7 ± 3.4	21.6 ± 2.6
			(p < 0.01)	(p < 0.01)