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Differential effects of monocarboxylates on DC development. A, Lin− bone marrow cells were cultured in the presence of GM-CSF (25 ng/ml) with and without different monocarboxylates (0.5 mm). After 6 days of culture, cells were analyzed for expression of CD11c and Gr-1 by flow cytometry. B, quantification of the effects of various monocarboxylates on the development of granulocytes and DCs.
