Table 2.
Characteristics of published studies on GSTP1I le105Val included in the meta-analysis
| Author (ref*) | Year | Origin | Ethnicity | SNPsite | Sample size(case/control) | HWE | MAF in controls | Genotypic ORs& | Power (%) † | |
|---|---|---|---|---|---|---|---|---|---|---|
| homozygotes/heterozygotes | OR>1.5 | OR>2.0 | ||||||||
| Lin DX&28 | 1998 | China | Asian | GSTP1 Ile105Val | 42/36 | 0.359 | 0.24 | 0.25/0.83 | 12.3 | 28.9 |
| Morita S29 | 1998 | Japan | Asian | GSTP1 Ile106Val | 66/164 | 0.412 | 0.16 | 0.26/0.19 | 19.2 | 49.2 |
| van Lieshout EM30 | 1999 | The Netherlands | Caucasian | GSTP1 Ile107Val | 34/247 | 0.739 | 0.23 | 3.65/3.44 | 16.4 | 40.7 |
| Tan W&31 | 2000 | China | Asian | GSTP1 Ile108Val | 150/150 | 0.616 | 0.22 | 1.47/0.89 | 33.5 | 77.1 |
| Lee JM22 | 2000 | China(Taiwan) | Asian | GSTP1 Ile109Val | 90/254 | NA# | NA# | NA#/ NA# | NA# | NA# |
| Casson AG21 | 2003 | Canada | Caucasian | GSTP1 Ile110Val | 45/45 | 0.019 | 0.29 | 0.78/2.51 | 14.6 | 35.1 |
| Roth MJ32 | 2004 | China | Asian | GSTP1 Ile111Val | 131/454 | 0.057 | 0.22 | 0.79/0.88 | 43.0 | 88.2 |
| Casson AG20 | 2006 | Canada | Caucasian | GSTP1 Ile112Val | 56/95 | 0.834 | 0.35 | 2.22/1.36 | 21.7 | 52.7 |
| Cai L25 | 2006 | China | Asian | GSTP1 Ile113Val | 204/393 | 0.872 | 0.18 | 0.46/0.93 | 48.4 | 92.6 |
| Murphy SJ33 | 2007 | Irish | Caucasian | GSTP1 Ile114Val | 207/223 | 0.201 | 0.36 | 0.99/0.93 | 54.0 | 94.4 |
| Canova C19 | 2009 | European | Caucasian | GSTP1 Ile115Val | 1471/1405 | 0.330 | 0.32 | 0.97/1.13 | 99.9 | 100.0 |
* The ref was referred to the reference numbers in this study.
& data from the same source, so selected by the latest sample size.
# NA: Not available.
&Genotypic odds ratios for homozygotes and heterozygotes.
† Power was calculated by the DSTPLAN4.2 software with MAF in controls as the frequency of risk factor, OR was selected 1.5 and 2.0 as the relative risk and а=0.05 as the significance.