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. 2010 Sep 1;7(5):300–308. doi: 10.7150/ijms.7.300

Table 3.

Summary ORs of p53 and GSTP1 polymorphisms and esophageal cancer risk

Comparison No. of Cases No. of Controls OR 95%CI P*
p53 Arg75Pro
Pro/Arg vs Arg/Arg 1761 2850 1.09 0.95-1.24 0.25
Pro/Pro vs Arg/Arg 1720 2263 1.43 1.23-1.68 0.06
Pro/Pro vs (Arg/Arg+Pro/Arg) 2919 4074 1.31 0.95-1.80 0.00
(Pro/Arg +Pro/Pro) vs Arg/Arg 2919 4074 1.20 1.06-1.36 0.08
GSTP1 Ile106Val
Ile/Val vs Ile/Ile 1687 1917 0.99 0.74-1.32 0.00
Val/Val vs Ile/Ile 1063 1295 1.00 0,81-1.23 0.28
Val/Val vs (Ile/Ile+Ile/Val) 1885 2194 0.95 0.79-1.17 0.57
(Ile/Val+Val/Val) vs Ile/Ile 1885 2194 0.95 0.73-1.25 0.00

* Test for heterogeneity. Fixed-effects model was used when P value for heterogeneity test > 0.05; otherwise, random-effects model was used.